Characterization of Essential Oils from Medicinal Plants and Assessment of Their Antimutagenic Effects Using Ames Salmonella/Microsomal Test

We investigated the antimutagenic activities and chemical compositionsof essential oil (EO) from Melissa officinalis, Lavandula angustifolia Origanum onites plants belonging to Lamiaceae family. The compositions of were determined by GC/MS analysis Ames assay was used in activity analysis. Citral, linalool, thymol terpinenes major components EOs M. L. O. onites. In assay, it that EO officinalis had strong effects at all concentrations except for highest on Salmonella typhimurium TA98 100 strains. showed moderate against Sodium azide (NaN3) mutagen, reduced mutant colonies with 25.40% inhibition effect S. TA100 strain only 0.1 μl/plate concentration. Furthermore, indicated both 4-Nitro-o-phenylendiamine (NPD) NaN3 mutagens strains 0.5 1 concentrations. It a lowest concentration other strain. 0.01, 0.05 present study demonstrated possesses